The Northumberland Development Project has been approved by London Mayor, Boris Johnson.
The new ground will hold 61,000 people and it will be fitted with a retractable pitch.
The stadium which is part of The Northumberland Development Project will hold two NFL fixtures as well as a number of concerts throughout the year.
Alongside the stadium, the complex will be home to a brand new 180-bed hotel, sports and health centre, and an interactive museum of the clubs history.
Developers plan to have the stadium finished ahead of the 2018/19 season.
London Mayor, Boris Johnson said: “White Hart Lane is already an iconic stadium, steeped in history.
“The new venue will not only almost double its capacity, but provide world-class facilities to watch Premier League football, international sports events and concerts in the heart of the capital.”